Cosmetic Research Department

Pursuing “Beautiful and Healthy Skin” Utilizing Lactic Acid Bacteria Fermentation Technology

The Cosmetic Research Department conducts evidence-based research and development on new cosmetics ingredients
based on dermatology and microbiology.
In addition, it carries out technical research in the blending of cosmetic ingredients into formulations such as lotions and creams.

Research areas

 - Development research into new cosmetic ingredients
 - Research into formulation technologies and application in products
 - Basic research into skin microbiota

Research on New Cosmetic Ingredients Based on Dermatology and Microbiology

 The Cosmetic Research Department explores Yakult's unique microbial fermentation ingredients that have various physiological effects, including moisturization, based on dermatology and lactic acid bacteria research. Moreover, it conducts research using fermentation engineering to enhance the productivity of beneficial substances.
 Yakult's original research started with founder Minoru Shirota's idea that "lactic acid bacteria function to protect the skin and the mucosa." This starting point has led to the creation of original ingredients, such as a lactic acid bacteria fermentation extract (Shirota Essence: S.E.), which comprises similar moisturizing agents as those found in the skin.

Development of cosmetic ingredients using fermentation technology (jar fermenter)
Development of cosmetic ingredients using fermentation technology (jar fermenter)

Yakult's Original Technological Development for Cosmetics and Research on Commercialization

 It also develops formulation technologies for creams, lotions and milky lotions to blend cosmetic ingredients that utilize beneficial microbes such as lactic acid bacteria and yeast, and natural substances. In addition, it applies formulation technology that utilizes physical chemistry and surface chemistry in the formulation of emulsifiers and lamellar vesicles (particles) which require a careful balance in blending.

Emulsification test and Rheometer
Emulsification test              Rheometer
Trial production of an emulsion at the intermediate plant
Trial production of an emulsion at the intermediate plant
Schematic of lamellar vesicles
Lamellar Particles
A moisturizing component consisting of a lamellar structure with an oil phase and an aqueous phase structurally similar to the intercellular lipids of healthy skin. It blends well with the skin and helps maintain its health.



 Inspired by the structure of intercellular lipids that help create healthy and beautiful skin, Yakult has developed lamellar particles using its proprietary formulation technology. These particles are used in our premium anti-aging skincare series Parabio. The technology that allows lamellar particles to retain a stable state in the products and to permeate the stratum corneum layer of the skin was born from a combination of many years of dermatological research and the latest formulation technology.

Researching the Utilization of Beneficial Microorganisms for Human Health

 Just as in food product development, the concept of utilizing beneficial microorganisms for human health is consistently applied in cosmetic product development as well.
 The Cosmetic Research Department also researches the relationship between the skin microbiota and skin health. It will continue to pursue the development of cosmetics unique to Yakult, grounded in decades of microbiological research.