Microbiological Research Department

Elucidating Microbial Physiology and Collecting and Supplying Beneficial Microbes

The Microbiological Research Department specializes in the research of microbes and elucidates physiology
which has yet to be clarified as well as converts newly discovered useful microbes into resources and applies them in product development.
In addition, it has the important task of supplying the seed cultures essential for the stable production of products.

Research areas

- Studies on function elucidation and nutrition of useful microorganisms
- Collection, storage and management of microbial resources
- Development of fermentation technologies and breeding of useful microorganisms
- Creation of useful strains based on genes and metabolic functions

Clarification of New Physiology in Probiotics

It also researches the functions of probiotics in the host from a microbial perspective and uses the latest technology to analyze the cooperative relationship between probiotics and intestinal bacteria. It is unclear how many bacteria are alive, where they are in the intestine, and what they are doing after consuming probiotics, but we are constantly in the pursuit of clarifying what the living bacteria are doing within the intestines.

L. casei strain Shirota
L. casei strain Shirota*
B.breve strain Yakult
B. breve strain Yakult
B.bifidum strain YIT 10347
B. bifidum strain YIT-10347

Yakult's Products are Born from a Massive Library of Microbes

It is impossible to readily build the enormous library of microbes developed with the steady efforts of predecessors and the technologies proprietary to Yakult, which has spent many years working with microbes, such as the one for isolating difficult-to-culture microorganisms. The library of microbes has an essential role of discovering next-generation probiotics and connecting them to the development of products, and has become the foundation supporting Yakult's proprietary research and development.

Collection of microorganisms, such as lactic acid bacteria and bifidobacteria
Collection of microorganisms, such as lactic acid bacteria and bifidobacteria

Supporting the Development of High Quality and Highly Functional Products at the Foundation

The Microbiological Research Department manages strains of microbes including L. casei strain Shirota* and provides seed cultures for plants inside and outside Japan. Without the supply of a safe, high quality seed culture, we cannot maintain our product's slogan of "quality that never changes anywhere." In addition, it utilizes original fermentation technology to not only improve quality and functionality, but also to make products more delicious.

Cultivation of anaerobic microbes in a glove box apparatus
Cultivation of anaerobic microbes in a glove box apparatus
Measurement of viable cell count by automatic colony counter
Measurement of viable cell count by automatic colony counter

*Classified as L. paracasei strain Shirota since April 2020.