Pharmaceutical Research Department

Research and Development of High-Value-Added Products Based on Microbiome Science

The role of the Pharmaceutical Research Department is to develop high-value-added products
that are based on microbiome science, contribute to the medical field, and are grounded in our own basic research.

Research areas

 - Exploratory research on bacterial strains with potential for disease prevention and treatment
 - Identification and elucidation of active components and their mechanisms of action
 - Research and development of formulations with medical applications
 - Functional verification of materials useful in animal healthcare and product development based on scientific evidence

It Began with the Anti-Cancer Properties of Lactic Acid Bacteria

 In 1978, it was discovered that the company's Lacticaseibacillus paracasei strain Shirota* exerts anti-cancer effects through immunostimulation. This breakthrough led to the launch of research and development efforts focused on anti-cancer drugs, and the company's pharmaceutical research expanded to include preventive medicine initiatives.
  *Previously classified as Lactobacillus casei strain Shirota

Research and Development of High-Value-Added Products for Medical Use Based on Microbiome Science

 A vast number of microorganisms inhabit the human mouth, skin, and intestines in the form of communities known as the microbiome (or microbial flora). Recent studies have revealed that the microbiome, particularly gut bacteria, is closely linked to various diseases. The Pharmaceutical Research Department works to elucidate the relationship between different diseases and the microbiome based on our proprietary basic research. Our goal is to develop high-value-added products that contribute to disease prevention, treatment, and the improvement of patients' quality of life (QOL).

Comprehensive Research Framework for Product Development

 The Pharmaceutical Research Department has established a comprehensive research framework and is equipped with advanced facilities that support product development in the medical field. Its research spans a wide spectrum: from basic studies, such as the exploration of novel materials based on microbiome research and the evaluation of their efficacy, to applied development. To contribute to the health of as many people as possible, the department actively promotes Yakult's distinctive approach to product development and scientific research.

A photo of sample preparation using a tablet press
Sample preparation using a tablet press
A photo of Nanoparticle Tracking Analysis System
Nanoparticle Tracking Analysis System